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Beta Defensin-2 Is Reduced in Central but Not in Distal Airways of Smoker COPD Patients
BACKGROUND: Altered pulmonary defenses in chronic obstructive pulmonary disease (COPD) may promote distal airways bacterial colonization. The expression/activation of Toll Like receptors (TLR) and beta 2 defensin (HBD2) release by epithelial cells crucially affect pulmonary defence mechanisms. METHO...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306426/ https://ncbi.nlm.nih.gov/pubmed/22438960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033601 |
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