Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma

BACKGROUND: The mammalian target of rapamycin (mTOR) protein is important for cellular growth and homeostasis. The presence and prognostic significance of inappropriate mTOR activation have been reported for several cancers. Mammalian target of rapamycin inhibitors, such as everolimus (RAD001), are...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Hirashima, K, Baba, Y, Watanabe, M, Karashima, R-I, Sato, N, Imamura, Y, Nagai, Y, Hayashi, N, Iyama, K-I, Baba, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
Soggetti:
Translational Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305959/
https://ncbi.nlm.nih.gov/pubmed/22333597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.36
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi