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The Nuclear Epidermal Growth Factor Receptor Signaling Network and its Role in Cancer

The epidermal growth factor receptor (EGFR) is a member of the EGFR family of receptor tyrosine kinases (RTKs). EGFR activation via ligand binding results in signaling through various pathways ultimately resulting in cellular proliferation, survival, angiogenesis, invasion, and metastasis. Aberrant...

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Detalhes bibliográficos
Main Authors: Brand, Toni M., Iida, Mari, Li, Chunrong, Wheeler, Deric L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305885/
https://ncbi.nlm.nih.gov/pubmed/22127113
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