TGF-β1 Down-Regulation of NKG2D/DAP10 and 2B4/SAP Expression on Human NK Cells Contributes to HBV Persistence

The mechanism underlying persistent hepatitis B virus (HBV) infection remains unclear. We investigated the role of innate immune responses to persistent HBV infection in 154 HBV-infected patients and 95 healthy controls. The expression of NKG2D- and 2B4-activating receptors on NK cells was significa...

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Detalhes bibliográficos
Main Authors: Sun, Cheng, Fu, Binqing, Gao, Yufeng, Liao, Xiaofeng, Sun, Rui, Tian, Zhigang, Wei, Haiming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305436/
https://ncbi.nlm.nih.gov/pubmed/22438812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002594
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