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The Traffic of the NKG2D/Dap10 Receptor Complex during Natural Killer (NK) Cell Activation

NKG2D is an important activating receptor for triggering the NK cell cytotoxic activity, although chronic engagement of specific ligands by NKG2D is also known to provoke decreased cell surface expression of the receptor and compromised NK cell function. We have studied the dynamics of surface NKG2D...

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Detalhes bibliográficos
Main Authors: Roda-Navarro, Pedro, Reyburn, Hugh T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713546/
https://ncbi.nlm.nih.gov/pubmed/19329438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808561200
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