Nos2 Inactivation Promotes the Development of Medulloblastoma in Ptch1(+/−) Mice by Deregulation of Gap43–Dependent Granule Cell Precursor Migration

Medulloblastoma is the most common malignant brain tumor in children. A subset of medulloblastoma originates from granule cell precursors (GCPs) of the developing cerebellum and demonstrates aberrant hedgehog signaling, typically due to inactivating mutations in the receptor PTCH1, a pathomechanism...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Haag, Daniel, Zipper, Petra, Westrich, Viola, Karra, Daniela, Pfleger, Karin, Toedt, Grischa, Blond, Frederik, Delhomme, Nicolas, Hahn, Meinhard, Reifenberger, Julia, Reifenberger, Guido, Lichter, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305407/
https://ncbi.nlm.nih.gov/pubmed/22438824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002572
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados