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Ribavirin restores ESR1 gene expression and tamoxifen sensitivity in ESR1 negative breast cancer cell lines

Tumor growth is estrogen independent in approximately one-third of all breast cancers, which makes these patients unresponsive to hormonal treatment. This unresponsiveness to hormonal treatment may be explained through the absence of the estrogen receptor alpha (ESR1). The ESR1 gene re-expression th...

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Detalhes bibliográficos
Main Authors: Sappok, Anne, Mahlknecht, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305339/
https://ncbi.nlm.nih.gov/pubmed/22414275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-3-8
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