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Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells

One third of all breast cancers are estrogen receptor alpha (ERα) negative, carry a poor overall prognosis, and do not respond well to currently available endocrine therapies. New treatment strategies are therefore required. Loss of Wnt-5a has previously been correlated with loss of ERα in clinical...

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Detalhes bibliográficos
Principais autores: Ford, Caroline E., Ekström, Elin J., Andersson, Tommy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656180/
https://ncbi.nlm.nih.gov/pubmed/19237581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809516106
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