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Transcription of adenovirus and HeLa cell genes in the presence of drugs that inhibit topoisomerase I and II function.
The requirements for topoisomerases in transcription of adenovirus and HeLa cell genes were analyzed using drugs that specifically inhibit either topoisomerases I or II. Cleavage of viral DNA by topoisomerases in the presence of either camptothecin or VM26 was used to determine drug concentrations t...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1990
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2158079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.6.1499 |
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