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Involvement of topoisomerases in replication, transcription, and packaging of the linear adenovirus genome.

The role of topoisomerases in the replication of human adenovirus type 5 was investigated with topoisomerase inhibitors. Both topoisomerase I and topoisomerase II inhibitors blocked adenovirus replication when added at the time of infection. Both types of inhibitors induced strand cleavages at speci...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Wong, M L, Hsu, M T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249162/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.691-699.1990
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