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Involvement of topoisomerases in replication, transcription, and packaging of the linear adenovirus genome.

The role of topoisomerases in the replication of human adenovirus type 5 was investigated with topoisomerase inhibitors. Both topoisomerase I and topoisomerase II inhibitors blocked adenovirus replication when added at the time of infection. Both types of inhibitors induced strand cleavages at speci...

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Detalhes bibliográficos
Main Authors: Wong, M L, Hsu, M T
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC249162/
https://ncbi.nlm.nih.gov/pubmed/2153235
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