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Transcription of adenovirus and HeLa cell genes in the presence of drugs that inhibit topoisomerase I and II function.

The requirements for topoisomerases in transcription of adenovirus and HeLa cell genes were analyzed using drugs that specifically inhibit either topoisomerases I or II. Cleavage of viral DNA by topoisomerases in the presence of either camptothecin or VM26 was used to determine drug concentrations t...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Schaak, J, Schedl, P, Shenk, T
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1990
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2158079/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.6.1499
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