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Transcription of adenovirus and HeLa cell genes in the presence of drugs that inhibit topoisomerase I and II function.
The requirements for topoisomerases in transcription of adenovirus and HeLa cell genes were analyzed using drugs that specifically inhibit either topoisomerases I or II. Cleavage of viral DNA by topoisomerases in the presence of either camptothecin or VM26 was used to determine drug concentrations t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1990
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC330517/ https://ncbi.nlm.nih.gov/pubmed/2158079 |
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