Amyloid-Like Fibril Formation by PolyQ Proteins: A Critical Balance between the PolyQ Length and the Constraints Imposed by the Host Protein

Nine neurodegenerative disorders, called polyglutamine (polyQ) diseases, are characterized by the formation of intranuclear amyloid-like aggregates by nine proteins containing a polyQ tract above a threshold length. These insoluble aggregates and/or some of their soluble precursors are thought to pl...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Scarafone, Natacha, Pain, Coralie, Fratamico, Anthony, Gaspard, Gilles, Yilmaz, Nursel, Filée, Patrice, Galleni, Moreno, Matagne, André, Dumoulin, Mireille
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305072/
https://ncbi.nlm.nih.gov/pubmed/22438863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031253
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker