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Computational modeling of the potential interactions of the proteasome β5 subunit and catechol-O-methyltransferase-resistant EGCG analogs
(−)-Epigallocatechin gallate [(−)-EGCG] has been implicated in cancer chemoprevention and has been shown as an inhibitor of tumor proteasomal chymotrypsin-like activity in vitro and in vivo. However, EGCG is subjected to rapid biotransforming modifications such as methylation by catechol-O-methyltra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3304469/ https://ncbi.nlm.nih.gov/pubmed/20596600 |
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