Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding.
We used energy minimization of a molecular mechanical force field to evaluate spermine interactions with B-form DNA oligomers with either alternating purine/pyrimidine or homopolymeric sequences. Four different positions for spermine docking--within, along, and bridging the minor groove and bridging...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1990
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330444/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2320418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.5.1271 |
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