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Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding.
We used energy minimization of a molecular mechanical force field to evaluate spermine interactions with B-form DNA oligomers with either alternating purine/pyrimidine or homopolymeric sequences. Four different positions for spermine docking--within, along, and bridging the minor groove and bridging...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
1990
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC330444/ https://ncbi.nlm.nih.gov/pubmed/2320418 |
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