Development of domperidone bilayered matrix type transdermal patches: physicochemical, in vitro and ex vivo characterization

BACKGROUND AND THE PURPOSE OF THE STUDY: Domperidone (DOM) is a dopamine- receptor (D(2)) antagonist, which is widely used in the treatment of motion-sickness. The pharmacokinetic parameters make DOM a suitable candidate for transdermal delivery. The purpose of the present investigation was to devel...

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Bibliographic Details
Main Authors: Madishetti, S.K., Palem, C.R., Gannu, R., Thatipamula, R.P., Panakanti, P.K., Yamsani, M.R.
Format: Artigo
Language:Inglês
Published: Tehran University of Medical Sciences 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304359/
https://ncbi.nlm.nih.gov/pubmed/22615620
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