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Development of domperidone bilayered matrix type transdermal patches: physicochemical, in vitro and ex vivo characterization
BACKGROUND AND THE PURPOSE OF THE STUDY: Domperidone (DOM) is a dopamine- receptor (D(2)) antagonist, which is widely used in the treatment of motion-sickness. The pharmacokinetic parameters make DOM a suitable candidate for transdermal delivery. The purpose of the present investigation was to devel...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Tehran University of Medical Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3304359/ https://ncbi.nlm.nih.gov/pubmed/22615620 |
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