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Optimization of Hydrogels for Transdermal Delivery of Lisinopril by Box–Behnken Statistical Design

The aim of this study was to investigate the combined influence of three independent variables on the permeation kinetics of lisinopril from hydrogels for transdermal delivery. A three-factor, three-level Box–Behnken design was used to optimize the independent variables, Carbopol 971 P (X(1)), menth...

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Detalhes bibliográficos
Main Authors: Gannu, Ramesh, Yamsani, Vamshi Vishnu, Yamsani, Shravan Kumar, Palem, Chinna Reddy, Yamsani, Madhusudan Rao
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690793/
https://ncbi.nlm.nih.gov/pubmed/19399627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9230-5
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