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Optimization of Hydrogels for Transdermal Delivery of Lisinopril by Box–Behnken Statistical Design
The aim of this study was to investigate the combined influence of three independent variables on the permeation kinetics of lisinopril from hydrogels for transdermal delivery. A three-factor, three-level Box–Behnken design was used to optimize the independent variables, Carbopol 971 P (X(1)), menth...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer US
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2690793/ https://ncbi.nlm.nih.gov/pubmed/19399627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9230-5 |
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