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Optimization of Hydrogels for Transdermal Delivery of Lisinopril by Box–Behnken Statistical Design

The aim of this study was to investigate the combined influence of three independent variables on the permeation kinetics of lisinopril from hydrogels for transdermal delivery. A three-factor, three-level Box–Behnken design was used to optimize the independent variables, Carbopol 971 P (X(1)), menth...

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Autori principali: Gannu, Ramesh, Yamsani, Vamshi Vishnu, Yamsani, Shravan Kumar, Palem, Chinna Reddy, Yamsani, Madhusudan Rao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690793/
https://ncbi.nlm.nih.gov/pubmed/19399627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9230-5
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