Constitutive Activation of Gαs within Forebrain Neurons Causes Deficits in Sensorimotor Gating Because of PKA-Dependent Decreases in cAMP

Sensorimotor gating, the ability to automatically filter sensory information, is deficient in a number of psychiatric disorders, yet little is known of the biochemical mechanisms underlying this critical neural process. Previously, we reported that mice expressing a constitutively active isoform of...

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Hauptverfasser: Kelly, Michele P., Isiegas, Carolina, Cheung, York-Fong, Tokarczyk, Jan, Yang, Xioaju, Esposito, Michael F., Rapoport, David A., Fabian, Sara A., Siegel, Steven J., Wand, Gary, Houslay, Miles D., Kanes, Stephen J., Abel, Ted
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303872/
https://ncbi.nlm.nih.gov/pubmed/16738544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301099
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