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A Cell-Based Small Molecule Screening Method for Identifying Inhibitors of Epithelial-Mesenchymal Transition in Carcinoma

Epithelial Mesenchymal Transition (EMT) is a crucial mechanism for carcinoma progression, as it provides routes for in situ carcinoma cells to dissociate and become motile, leading to localized invasion and metastatic spread. Targeting EMT therefore represents an important therapeutic strategy for c...

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Autors principals: Chua, Kian-Ngiap, Sim, Wen-Jing, Racine, Victor, Lee, Shi-Yun, Goh, Boon Cher, Thiery, Jean Paul
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303807/
https://ncbi.nlm.nih.gov/pubmed/22432005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033183
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