Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

The epithelial-mesenchymal transition (EMT) has been implicated in conferring stem cell properties and therapeutic resistance to cancer cells. Therefore, identification of drugs that can reprogram EMT may provide new therapeutic strategies. Here, we report that cells derived from claudin-low mammary...

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發表在:Nat Commun
Main Authors: Zhao, Na, Powell, Reid T., Yuan, Xueying, Bae, Goeun, Roarty, Kevin P., Stossi, Fabio, Strempfl, Martina, Toneff, Michael J., Johnson, Hannah L., Mani, Sendurai A., Jones, Philip, Stephan, Clifford C., Rosen, Jeffrey M.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275587/
https://ncbi.nlm.nih.gov/pubmed/34253738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24545-3
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