Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

The epithelial-mesenchymal transition (EMT) has been implicated in conferring stem cell properties and therapeutic resistance to cancer cells. Therefore, identification of drugs that can reprogram EMT may provide new therapeutic strategies. Here, we report that cells derived from claudin-low mammary...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Zhao, Na, Powell, Reid T., Yuan, Xueying, Bae, Goeun, Roarty, Kevin P., Stossi, Fabio, Strempfl, Martina, Toneff, Michael J., Johnson, Hannah L., Mani, Sendurai A., Jones, Philip, Stephan, Clifford C., Rosen, Jeffrey M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275587/
https://ncbi.nlm.nih.gov/pubmed/34253738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24545-3
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