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Identifying Inhibitors of Epithelial-Mesenchymal Transition by Connectivity-Map Based Systems Approach
BACKGROUND: Acquisition of mesenchymal phenotype by epithelial cells by means of epithelial mesenchymal transition (EMT) is considered as an early event in the multi-step process of tumor metastasis. Therefore, inhibition of EMT might be a rational strategy to prevent metastasis. METHODS: Utilizing...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196823/ https://ncbi.nlm.nih.gov/pubmed/21964532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31822adfb0 |
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