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Identifying Inhibitors of Epithelial-Mesenchymal Transition by Connectivity-Map Based Systems Approach

BACKGROUND: Acquisition of mesenchymal phenotype by epithelial cells by means of epithelial mesenchymal transition (EMT) is considered as an early event in the multi-step process of tumor metastasis. Therefore, inhibition of EMT might be a rational strategy to prevent metastasis. METHODS: Utilizing...

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Hlavní autoři: Reka, Ajaya Kumar, Kuick, Rork, Kurapati, Himabindu, Standiford, Theodore J., Omenn, Gilbert S., Keshamouni, Venkateshwar G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196823/
https://ncbi.nlm.nih.gov/pubmed/21964532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31822adfb0
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