Development of Tyrosine-Based Radiotracer (99m)Tc-N4-Tyrosine for Breast Cancer Imaging

The purpose of this study was to develop an efficient way to synthesize (99m)Tc-O-[3-(1,4,8,11-tetraazabicyclohexadecane)-propyl]-tyrosine ((99m)Tc-N4-Tyrosine), a novel amino acid-based radiotracer, and evaluate its potential in breast cancer gamma imaging. Precursor N4-Tyrosine was synthesized usi...

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Main Authors: Kong, Fan-Lin, Ali, Mohammad S., Rollo, Alex, Smith, Daniel L., Zhang, Yinhan, Yu, Dong-Fang, Yang, David J.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303751/
https://ncbi.nlm.nih.gov/pubmed/22496612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/671708
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