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Synthesis and Evaluation of Amino Acid-Based Radiotracer (99m)Tc-N4-AMT for Breast Cancer Imaging
Purpose. This study was to develop an efficient synthesis of (99m)Tc-O-[3-(1,4,8,11-tetraazabicyclohexadecane)-propyl]-α-methyl tyrosine ((99m)Tc-N4-AMT) and evaluate its potential in cancer imaging. Methods. N4-AMT was synthesized by reacting N4-oxalate and 3-bromopropyl AMT (N-BOC, ethyl ester). I...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085329/ https://ncbi.nlm.nih.gov/pubmed/21541217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/276907 |
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