Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes - a study in humans and rats: Despa; Cardiotoxicity of Hyperamylinemia

RATIONALE: Hyperamylinemia is common in patients with obesity and insulin resistance, coincides with hyperinsulinemia, and results in amyloid deposition. Amylin amyloids are generally considered a pancreatic disorder in type-2 diabetes. However, elevated circulating levels of amylin may also lead to...

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Autors principals: Despa, Sanda, Margulies, Kenneth B., Chen, Le, Knowlton, Anne A., Havel, Peter J., Taegtmeyer, Heinrich, Bers, Donald M., Despa, Florin
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303627/
https://ncbi.nlm.nih.gov/pubmed/22275486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.258285
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