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The structure of a pre-mRNA molecule in solution determined with a site directed cross-linking reagent.
We describe the use of site specific psoralen (SSP) to determine the solution structure of a segment of the human beta globin pre-mRNA. In these experiments, SSP is first delivered as monoadducts to specific nucleotides in the pre-mRNA and subsequently used to form intramolecular RNA-RNA cross-links...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
1990
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| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC330337/ https://ncbi.nlm.nih.gov/pubmed/2315042 |
| Clibeanna: |
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