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The structure of a pre-mRNA molecule in solution determined with a site directed cross-linking reagent.

We describe the use of site specific psoralen (SSP) to determine the solution structure of a segment of the human beta globin pre-mRNA. In these experiments, SSP is first delivered as monoadducts to specific nucleotides in the pre-mRNA and subsequently used to form intramolecular RNA-RNA cross-links...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Teare, J, Wollenzien, P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 1990
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2315042/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.4.855
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