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Sanggenon C decreases tumor cell viability associated with proteasome inhibition

Several flavonoids have been reported to be proteasome inhibitors, but whether prenylated flavonoids are able to inhibit proteasome function remains unknown. We report for the first time that Sanggenon C, a natural prenylated flavonoid, inhibits tumor cellular proteasomal activity and cell viability...

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Detalhes bibliográficos
Main Authors: Huang, Hongbiao, Liu, Ningning, Zhao, Kai, Zhu, Chenchen, Lu, Xiaoyu, Li, Shujue, Lian, Wen, Zhou, Ping, Dong, Xiaoxian, Zhao, Canguo, Guo, Haiping, Zhang, Change, Yang, Changshan, Wen, Guanmei, Lu, Li, Li, Xiaofen, Guan, Lixia, Liu, Chunjiao, Wang, Xuejun, Dou, Qing Ping, Liu, Jinbao
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303154/
https://ncbi.nlm.nih.gov/pubmed/21622138
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