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Sanggenon C decreases tumor cell viability associated with proteasome inhibition

Several flavonoids have been reported to be proteasome inhibitors, but whether prenylated flavonoids are able to inhibit proteasome function remains unknown. We report for the first time that Sanggenon C, a natural prenylated flavonoid, inhibits tumor cellular proteasomal activity and cell viability...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Hongbiao, Liu, Ningning, Zhao, Kai, Zhu, Chenchen, Lu, Xiaoyu, Li, Shujue, Lian, Wen, Zhou, Ping, Dong, Xiaoxian, Zhao, Canguo, Guo, Haiping, Zhang, Change, Yang, Changshan, Wen, Guanmei, Lu, Li, Li, Xiaofen, Guan, Lixia, Liu, Chunjiao, Wang, Xuejun, Dou, Qing Ping, Liu, Jinbao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303154/
https://ncbi.nlm.nih.gov/pubmed/21622138
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