Inhibition of Tumor Cellular Proteasome Activity by Triptolide Extracted from the Chinese Medicinal Plant ‘Thunder God Vine’

AIMS: The molecular mechanisms of triptolide responsible for its antitumor properties are not yet fully understood. The ubiquitin/proteasome system is an important pathway of protein degradation in cells. This study investigated whether triptolide may inhibit proteasomal activity and induce apoptosi...

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Hauptverfasser: LU, LI, KANWAR, JYOTI, SCHMITT, SARA, CUI, QIUZHI CINDY, ZHANG, CHUANYIN, ZHAO, CONG, DOU, Q. PING
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303151/
https://ncbi.nlm.nih.gov/pubmed/21273574
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