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High-throughput decoding of anti-trypanosomal drug efficacy and resistance

The concept of specific chemotherapy was developed a century ago by Paul Ehrlich and others. Dyes and arsenical compounds that displayed selectivity against trypanosomes were central to this work (1,2), and the drugs that emerged remain in use for treating Human African Trypanosomiasis (HAT) (3). Eh...

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Hlavní autoři: Alsford, Sam, Eckert, Sabine, Baker, Nicola, Glover, Lucy, Sanchez-Flores, Alejandro, Leung, Ka Fai, Turner, Daniel J., Field, Mark C., Berriman, Matthew, Horn, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303116/
https://ncbi.nlm.nih.gov/pubmed/22278056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10771
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