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High-throughput decoding of anti-trypanosomal drug efficacy and resistance
The concept of specific chemotherapy was developed a century ago by Paul Ehrlich and others. Dyes and arsenical compounds that displayed selectivity against trypanosomes were central to this work (1,2), and the drugs that emerged remain in use for treating Human African Trypanosomiasis (HAT) (3). Eh...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3303116/ https://ncbi.nlm.nih.gov/pubmed/22278056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10771 |
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