High-throughput decoding of anti-trypanosomal drug efficacy and resistance

The concept of specific chemotherapy was developed a century ago by Paul Ehrlich and others. Dyes and arsenical compounds that displayed selectivity against trypanosomes were central to this work (1,2), and the drugs that emerged remain in use for treating Human African Trypanosomiasis (HAT) (3). Eh...

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Библиографические подробности
Главные авторы: Alsford, Sam, Eckert, Sabine, Baker, Nicola, Glover, Lucy, Sanchez-Flores, Alejandro, Leung, Ka Fai, Turner, Daniel J., Field, Mark C., Berriman, Matthew, Horn, David
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303116/
https://ncbi.nlm.nih.gov/pubmed/22278056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10771
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