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Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase
Diurnal phagocytosis of shed photoreceptor outer-segment particles by retinal pigment epithelial (RPE) cells belongs to a group of conserved clearance mechanisms employing αv integrins upstream of tyrosine kinases and Rho GTPases. In this study, we tested the interdependence of the tyrosine kinases...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302737/ https://ncbi.nlm.nih.gov/pubmed/22262456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0840 |
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