Phosphorylated α-Synuclein in Parkinson’s Disease

Phosphorylated α-synuclein (PS-129), a protein implicated in the pathogenesis of Parkinson’s disease (PD), was identified by mass spectrometry in human cerebrospinal fluid (CSF). A highly sensitive and specific assay was established and used to measure PS-129, along withtotal α-synuclein, in the CSF...

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Detalhes bibliográficos
Main Authors: Wang, Yu, Shi, Min, Chung, Kathryn A., Zabetian, Cyrus P., Leverenz, James B., Berg, Daniela, Srulijes, Karin, Trojanowski, John Q., Lee, Virginia M.-Y., Siderowf, Andrew D., Hurtig, Howard, Litvan, Irene, Schiess, Mya C., Peskind, Elaine R., Masuda, Masami, Hasegawa, Masato, Lin, Xiangmin, Pan, Catherine, Galasko, Douglas, Goldstein, David S., Jensen, Poul Henning, Yang, Hui, Cain, Kevin C., Zhang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302662/
https://ncbi.nlm.nih.gov/pubmed/22344688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002566
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