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Phosphorylated α-Synuclein in Parkinson’s Disease

Phosphorylated α-synuclein (PS-129), a protein implicated in the pathogenesis of Parkinson’s disease (PD), was identified by mass spectrometry in human cerebrospinal fluid (CSF). A highly sensitive and specific assay was established and used to measure PS-129, along withtotal α-synuclein, in the CSF...

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Main Authors: Wang, Yu, Shi, Min, Chung, Kathryn A., Zabetian, Cyrus P., Leverenz, James B., Berg, Daniela, Srulijes, Karin, Trojanowski, John Q., Lee, Virginia M.-Y., Siderowf, Andrew D., Hurtig, Howard, Litvan, Irene, Schiess, Mya C., Peskind, Elaine R., Masuda, Masami, Hasegawa, Masato, Lin, Xiangmin, Pan, Catherine, Galasko, Douglas, Goldstein, David S., Jensen, Poul Henning, Yang, Hui, Cain, Kevin C., Zhang, Jing
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302662/
https://ncbi.nlm.nih.gov/pubmed/22344688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002566
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