Phosphorylated α-Synuclein in Parkinson’s Disease

Phosphorylated α-synuclein (PS-129), a protein implicated in the pathogenesis of Parkinson’s disease (PD), was identified by mass spectrometry in human cerebrospinal fluid (CSF). A highly sensitive and specific assay was established and used to measure PS-129, along withtotal α-synuclein, in the CSF...

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Main Authors: Wang, Yu, Shi, Min, Chung, Kathryn A., Zabetian, Cyrus P., Leverenz, James B., Berg, Daniela, Srulijes, Karin, Trojanowski, John Q., Lee, Virginia M.-Y., Siderowf, Andrew D., Hurtig, Howard, Litvan, Irene, Schiess, Mya C., Peskind, Elaine R., Masuda, Masami, Hasegawa, Masato, Lin, Xiangmin, Pan, Catherine, Galasko, Douglas, Goldstein, David S., Jensen, Poul Henning, Yang, Hui, Cain, Kevin C., Zhang, Jing
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302662/
https://ncbi.nlm.nih.gov/pubmed/22344688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002566
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