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HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6
The antiviral factor CPSF6-358 restricts human immunodeficiency virus type 1 (HIV-1) infection through an interaction with capsid (CA), preventing virus nuclear entry and integration. HIV-1 acquires resistance to CPSF6-358 through an N74D mutation of CA that impairs binding of the antiviral factor....
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302544/ https://ncbi.nlm.nih.gov/pubmed/22301135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06607-11 |
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