Deletions in the Neuraminidase Stalk Region of H2N2 and H9N2 Avian Influenza Virus Subtypes Do Not Affect Postinfluenza Secondary Bacterial Pneumonia

We investigated the synergism between influenza virus and Streptococcus pneumoniae, particularly the role of deletions in the stalk region of the neuraminidase (NA) of H2N2 and H9N2 avian influenza viruses. Deletions in the NA stalk (ΔNA) had no effect on NA activity or on the adherence of S. pneumo...

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Main Authors: Chockalingam, Ashok K., Hickman, Danielle, Pena, Lindomar, Ye, Jianqiang, Ferrero, Andrea, Echenique, Jose R., Chen, Hongjun, Sutton, Troy, Perez, Daniel R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302490/
https://ncbi.nlm.nih.gov/pubmed/22278240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05809-11
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