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A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling

Copper (Cu) is essential for development and proliferation, yet the cellular requirements for Cu in these processes are not well defined. We report that Cu plays an unanticipated role in the mitogen-activated protein (MAP) kinase pathway. Ablation of the Ctr1 high-affinity Cu transporter in flies an...

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Detalhes bibliográficos
Main Authors: Turski, Michelle L., Brady, Donita C., Kim, Hyung J., Kim, Byung-Eun, Nose, Yasuhiro, Counter, Christopher M., Winge, Dennis R., Thiele, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302449/
https://ncbi.nlm.nih.gov/pubmed/22290441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05722-11
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