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Role of β-Catenin and TCF/LEF Family Members in Transcriptional Activity of HIV in Astrocytes

The Wnt/β-catenin pathway is involved in diverse cell functions governing development and disease. β-Catenin, a central mediator of this pathway, binds to members of the TCF/LEF family of transcription factors to modulate hundreds of genes. Active Wnt/β-catenin/TCF-4 signaling plays a significant ro...

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Détails bibliographiques
Auteurs principaux: Narasipura, Srinivas D., Henderson, Lisa J., Fu, Sidney W., Chen, Liang, Kashanchi, Fatah, Al-Harthi, Lena
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302377/
https://ncbi.nlm.nih.gov/pubmed/22156527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06266-11
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