A Human Antibody Recognizing a Conserved Epitope of H5 Hemagglutinin Broadly Neutralizes Highly Pathogenic Avian Influenza H5N1 Viruses

Influenza A virus infection is a persistent threat to public health worldwide due to its ability to evade immune surveillance through rapid genetic drift and shift. Current vaccines against influenza A virus provide immunity to viral isolates that are similar to vaccine strains. High-affinity neutra...

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Main Authors: Hu, Hongxing, Voss, Jarrod, Zhang, Guoliang, Buchy, Philippi, Zuo, Teng, Wang, Lulan, Wang, Feng, Zhou, Fan, Wang, Guiqing, Tsai, Cheguo, Calder, Lesley, Gamblin, Steve J., Zhang, Linqi, Deubel, Vincent, Zhou, Boping, Skehel, John J., Zhou, Paul
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302345/
https://ncbi.nlm.nih.gov/pubmed/22238297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06665-11
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