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Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: Novel insights into autoantigen selection in rheumatoid arthritis

OBJECTIVE: To define the relationship between autoantigen citrullination and different peptidylarginine deiminase (PAD) enzymes in rheumatoid arthritis (RA). METHODS: Citrullinated autoantigens were identified by immunoblotting control and ionomycin-activated human primary neutrophil lysate with RA...

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Библиографические подробности
Главные авторы: Darrah, Erika, Rosen, Antony, Giles, Jon T., Andrade, Felipe
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302156/
https://ncbi.nlm.nih.gov/pubmed/21859690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2011.151712
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