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Peptidylarginine deiminase type 2 and 4 generate distinct patterns of rheumatoid arthritis autoantigens during perforin-induced cell damage
OBJECTIVE: To address the independent role of peptidylarginine deiminase type 2 and 4 (PAD2 and PAD4, respectively) in generating rheumatoid arthritis (RA) autoantigens by using a system that mimics intracellular citrullination in the RA joint. METHODS: 293T cells expressing PAD2, PAD4 or mock trans...
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| Publié dans: | Arthritis Rheumatol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7255925/ https://ncbi.nlm.nih.gov/pubmed/31876120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41196 |
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