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Peptidylarginine deiminase type 2 and 4 generate distinct patterns of rheumatoid arthritis autoantigens during perforin-induced cell damage

OBJECTIVE: To address the independent role of peptidylarginine deiminase type 2 and 4 (PAD2 and PAD4, respectively) in generating rheumatoid arthritis (RA) autoantigens by using a system that mimics intracellular citrullination in the RA joint. METHODS: 293T cells expressing PAD2, PAD4 or mock trans...

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書目詳細資料
發表在:Arthritis Rheumatol
Main Authors: Romero, Violeta, Darrah, Erika, Andrade, Felipe
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255925/
https://ncbi.nlm.nih.gov/pubmed/31876120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41196
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