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Human ApoA-II inhibits the hydrolysis of HDL triglyceride and the decrease of HDL size induced by hypertriglyceridemia and cholesteryl ester transfer protein in transgenic mice.

The plasma cholesteryl ester transfer protein (CETP) mediates the exchange of HDL cholesteryl esters with triglycerides of other lipoproteins. Subsequent lipolysis of the triglyceride-enriched HDL by hepatic lipase leads to reductions of HDL size and apoA-I content. To investigate a possible modulat...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Zhong, S, Goldberg, I J, Bruce, C, Rubin, E, Breslow, J L, Tall, A
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7989603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117614
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