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Intravenous injection of apoA-V reconstituted HDL decreases hypertriglyceridemia in apoav-/- mice and requires GPIHBP1

OBJECTIVE: Apolipoprotein A-V (apoA-V), a minor protein associated with lipoproteins, has a major effect on triacylglycerol (TG) metabolism. We investigated whether apoA-V complexed with phospholipid in the form of a reconstituted HDL (rHDL) has potential utility as a therapeutic agent for treatment...

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Main Authors: Shu, Xiao, Nelbach, Lisa, Weinstein, Michael M., Burgess, Braydon L., Beckstead, Jennifer A., Young, Stephen G., Ryan, Robert O., Forte, Trudy M.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988087/
https://ncbi.nlm.nih.gov/pubmed/20966404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.210815
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