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Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53
Chemotherapy is the bedrock for the clinical management of cancer, and the tumor suppressor p53 has a central role in this therapeutic modality. This protein facilitates favorable antitumor drug response through a variety of key cellular functions, including cell cycle arrest, senescence, and apopto...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299825/ https://ncbi.nlm.nih.gov/pubmed/22227014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.12.026 |
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