Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

Docosahexaenoic acid (DHA) has been reported to induce tumor cell death by apoptosis. However, little is known about the effects of DHA on autophagy, another complex well-programmed process characterized by the sequestration of cytoplasmic material within autophagosomes. Here we show that DHA increa...

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Detalhes bibliográficos
Main Authors: Jing, Kaipeng, Song, Kyoung-Sub, Shin, Soyeon, Kim, Nayeong, Jeong, Soyeon, Oh, Hye-Rim, Park, Ji-Hoon, Seo, Kang-Sik, Heo, Jun-Young, Han, Jeongsu, Park, Jong-Il, Han, Chang, Wu, Tong, Kweon, Gi-Ryang, Park, Seung-Kiel, Yoon, Wan-Hee, Hwang, Byung-Doo, Lim, Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242799/
https://ncbi.nlm.nih.gov/pubmed/21811093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.11.16658
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