p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients

INTRODUCTION: Normal function of the p53 network is lost in most cancers, often through p53 mutation. The clinical impact of p53 mutations in breast cancer remains uncertain, especially where p53 isoforms may modify the effects of these p53 mutations. METHODS: Expression of p53β and p53γ isoforms, t...

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Main Authors: Bourdon, Jean-Christophe, Khoury, Marie P, Diot, Alexandra, Baker, Lee, Fernandes, Kenneth, Aoubala, Mustapha, Quinlan, Philip, Purdie, Colin A, Jordan, Lee B, Prats, Anne-Catherine, Lane, David P, Thompson, Alastair M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109573/
https://ncbi.nlm.nih.gov/pubmed/21251329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2811
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