Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein I.

It has been reported that antiphospholipid autoantibodies do not recognize phospholipid alone, but rather the plasma protein beta 2-glycoprotein I (beta 2GPI), or a beta 2GPI-phospholipid complex. In vitro beta 2GPI binds to anionic phospholipids and inhibits the prothrombinase activity of procoagul...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Roubey, R A, Pratt, C W, Buyon, J P, Winfield, J B
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1522218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115926
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