Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein I.

It has been reported that antiphospholipid autoantibodies do not recognize phospholipid alone, but rather the plasma protein beta 2-glycoprotein I (beta 2GPI), or a beta 2GPI-phospholipid complex. In vitro beta 2GPI binds to anionic phospholipids and inhibits the prothrombinase activity of procoagul...

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Bibliografische gegevens
Hoofdauteurs: Roubey, R A, Pratt, C W, Buyon, J P, Winfield, J B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC329970/
https://ncbi.nlm.nih.gov/pubmed/1522218
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