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Molecular Mechanochemistry: Low force switch slows enzymatic cleavage of human type I collagen monomer

In vertebrate animals, fibrillar collagen accumulates, organizes and persists in structures which resist mechanical force. This anti-dissipative behavior is possibly due to a mechanochemical force-switch which converts collagen from enzyme-susceptible to enzyme-resistant. Degradation experiments on...

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Bibliographische Detailangaben
Hauptverfasser: Camp, Robert J., Liles, Melody, Beale, John, Saeidi, Nima, Flynn, Brendan P., Moore, Elias, Murthy, Shashi K., Ruberti, Jeffrey W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299535/
https://ncbi.nlm.nih.gov/pubmed/21348512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110098b
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